Sequencing is hard, slow, and expensive. Why not
screen your potential site directed mutants with simple restriction
digests instead? Use MutantMaker to design oligonucleotides
that will create or destroy restriction sites while also
creating the mutation you want!
MutantMaker helps researchers performing
site directed mutagenesis screen their potential mutants with
restriction enzyme digests rather than costly sequencing. The
oligonucleotide sequences suggested by MutantMaker will create or
destroy restriction sites while both creating the desired mutant and
retaining flanking amino acids.
Using a simple and elegant user interface, researchers enter their
original DNA sequence into a text field, drag a codon selector over the
codon to mutate, and choose how to mutate their selected amino acid.
MutantMaker has 492 unique restriction enzymes built right in, not
including isoschizomers! Users can select any set of enzymes based on
commercial availability or size.
MutantMaker results are even multi-colored showing exactly which
nucleotides were mutated.
In typical fashion, results can be saved and reloaded for later use.
And for reliability, data files are human-readable XML.
We work very hard to provide you with high quality software.
Download our software for free - if you like it and wish to continue
using it, purchase it online from our Purchase Page. There you'll find
information about multiple copy discounts and a price list for all of
our products. Your payments will help us offer you even more!
